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Using Regenerative Medicine for Orthopaedic Injuries

At Wake Orthopaedics, our non-operative interventional orthopaedics team is on the frontier of cutting-edge technology. Using the body’s natural healing properties, we offer many new technologies and treatments for orthopaedic conditions including platelet-rich therapy (PRP), Alpha-2-Macroglobulin (A2M) and stem cell therapies.

Interventional orthopaedics is helping many athletes and active people who suffer from orthopaedic conditions recover faster and, oftentimes, avoid the need for surgery. Our interventional ortho team is fellowship-trained in ultrasound guidance for precision placement and has years of experience navigating the natural healing landscape.


Healing From the Inside Out

Regenerative medicine treatments can provide significant relief of pain and improvement in function. At Wake Orthopaedics, we offer a variety of treatment options including:

Platelet-rich plasma (PRP Therapy): PRP therapy is a form of orthobiologics which takes advantage of the blood’s natural healing properties. The procedure involves taking a blood sample from the patient, just like you would give blood for labs at your doctor’s office. The blood is then separated through centrifuge techniques in a way to concentrate the platelets and growth factors to yield platelet-rich plasma. The isolated PRP is then made ready for injection back into the body at and around the point of injury or pain. When concentrated platelets and growth factors interact with the local cells, they trigger the process that promotes soft tissue healing as well as lower recovery time.




Stem Cell Therapy: Like PRP therapy, interventional orthopaedic stem cell therapy is designed to boost the body’s own ability for healing. Stem cells are undifferentiated cells that can become many different types of cells including cartilage, muscles, nerve or other cells. They are harvested from the bone marrow as bone marrow aspirate or from adipose cells in the form of a mini liposuction technique. These cells are then mechanized and made ready for injection back into the body.

Alpha-2-Macroglobulin (A2M Therapy): Additionally, Alpha-2-Macroglobulin (A2M) therapy helps to treat and inhibit osteoarthritis and joint pain. A2M is a naturally occurring protein found in blood plasma, known for its powerful ability to inhibit cartilage breakdown and neutralize inflammatory enzymes. By isolating and concentrating A2M from a blood sample, we create a personalized therapeutic injection.

Prolotherapy, cord blood and amniotic fluid therapies are available upon further discussion with Wake Orthopaedic’s interventional orthopaedic team.

We Treat a Range of Conditions

Regenerative medicine treatments such as PRP, A2M and orthopaedic stem cell therapies can be used to treat many orthopaedic injuries and conditions, including:

  • Arthritis or osteoarthritis
  • Articular cartilage injury
  • Muscle strains
  • Running injuries
  • Tendonitis
  • Tendon or ligament injury (tear, sprain)
  • Trauma or impact injuries

Depending on the location of the injury or condition being treated, ultrasound guidance is typically used by our fellowship-trained physicians to allow for accurate delivery of the body’s healing products. This is very important in gaining the planned result for many patients.

These therapies are performed as a same day, office-based procedure with minimal downtime, and can often improve pain and function tremendously. Interventional orthopaedic therapies may not be covered by insurance. If you are considering interventional orthopaedic therapy, it is important to contact your insurance carrier to determine coverage and at what cost. Consultations are covered can be scheduled and paid for through your regular insurance plan.

These therapies are performed as a same day, office-based procedure with minimal downtime, and can often improve pain and function tremendously.

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Our Providers

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At Wake Orthopaedics, it’s our goal to ensure you receive the best care possible, and that may be with a different provider than you originally selected due to their area of specialization. Answer a few questions and we’ll pair you with a Wake Orthopaedics provider that best fits your needs.