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To protect the health and wellbeing of our community, no visitors are allowed into our hospitals until further notice.
Limited exceptions may be made. Learn more.

Now offering virtual visits for all WakeMed Physician Practice primary care and specialties locations. Schedule an appointment today.

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Matthew Lyons, MD

WakeMed Physician Practices providers
Practice Name
WakeMed Physician Practices - Urology
Hospital Preference
WakeMed Cary Hospital
WakeMed Raleigh Campus
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We are pleased to offer our valued patients the ability to schedule an appointment online, 24 hours a day, 7 days a week without ever picking up the phone. As always, if you don't see an appointment time or type that works for you, please contact our office directly so we can help.

New Patients:

Simply choose your physician, preferred location and type of visit, and select the appointment time that works best for you.

Established Patients:

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Office Location
Urology - East Raleigh
23 Sunnybrook Road
WakeMed Raleigh Medical Park, Suite 310
Raleigh, NC 27610
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Office Location
Urology - Garner
400 US Highway 70 East
WakeMed Garner Healthplex, Suite 205
Garner, NC 27529
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Robotic and minimally invasive surgery for prostate cancer
Kidney cancer
Urothelial cancer
Urinary tract reconstruction
Advanced minimally invasive techniques for the management of urinary stone disease and enlarged prostate (BPH)
Treatment of men’s health issues including vasectomy consultation, low testosterone, erectile dysfunction and Peyronie’s disease, including prosthetic surgery
Undergraduate Degree
Washington and Lee University, Lexington, VA (Biology)
Medical School
Eastern Virginia Medical School, Norfolk, VA
University of North Carolina Hospitals, Chapel Hill, NC (General Surgery)
University of North Carolina Hospitals, Chapel Hill, NC (Urology)
American Board of Urology (Eligible)
Professional Memberships
Endourological Society
American Urological Association
Patient Care Philosophy
“I believe in the relentless pursuit of exceptional patient care; the same care I would expect for myself or my family”

Dr. Matthew Lyons is a urologist who specializes in minimally invasive and advanced robotic surgical techniques for the treatment of genitourinary cancers, benign prostate enlargement and urinary stone disease. He is an active participant in the Wake County GU oncology tumor board, which allows for a state of the art, multi-disciplinary approach to cancer treatment and collaboration with Duke medical oncologists, radiologists and radiation oncologists. This allows his patients access to cutting edge cancer care right here in Wake County. 

Additionally, Dr. Lyons specializes in men's health issues and offers advanced treatments for erectile dysfunction including prosthetic surgery, curvature of the penis (Peyronie's disease), including plication surgery and intralesional injection therapy with Xiaflex as well as treatment of low testosterone. Dr. Lyons also offers minimally invasive, single-incision, no scalpel vasectomy.

After graduating from medical school, Dr. Lyons continued his training by completing an internship in general surgery, and a residency in urology at the University of North Carolina at Chapel Hill. Dr. Lyons has published numerous research documents and abstracts on a wide range of urologic diseases and has presented his work at national and international meetings.


Dr. Lyons enjoys spending time with his family and his golden retriever "Ned", in addition to cheering on the Hurricanes and performing live music.?

"I believe in the relentless pursuit of exceptional patient care; the same care I would expect for myself or my family. I practice evidence-based urology and utilize the most recent advances in technology and clinical research to provide state of the art care to my patients.”

Insurance We Accept

WakeMed contracts with most major health insurance carriers. View a list of Insurance we accept.

Before scheduling an appointment with either a WakeMed employed provider or a community-based affiliated physician, we encourage you to contact your insurance company to verify that the location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co-insurances, or deductibles that will be your responsibility.

If you are uninsured, learn more about WakeMed's financial assistance policy.

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