Fecal Microbiota Transplantation to Treat Recurrent Clostridium Difficile Infection
WakeMed is the only hospital in Wake County , N.C., to offer Fecal Microbiota Transplantation (FMT) for recurrent Clostridium difficile (C. diff) infection. FMT is now available at WakeMed for the children and adults with recurrent C. diff infection.
C. diff is a normal, usually harmless bacterium that exists in the intestine. However, if this healthy balance of good and harmful bacteria is disrupted in a person’s intestines (such as by taking antibiotics), it can result in a C. diff infection.
Other potential causes of C. diff infection include:
C. diff can also be spread from person to person, especially if a healthcare provider touches a contaminated surface and then touches a patient.
There are many uncomfortable symptoms associated with C. diff, including diarrhea (sometimes bloody), stomach pain, fever, and even appetite and weight loss. Prolonged diarrhea can cause an inflamed colon, or colitis, which creates even more health complications. Treatment for C. diff is typically antibiotics, which sometimes do not work. Many patients who develop C. Diff infection, can have recurrence of C. diff and do not respond to standard medical therapy. Therefore, a new alternative treatment could be the better answer for your child – Fecal Microbiota Transplant (FMT).
Dr. Sachin Kunde of WakeMed Physician Practices – is experienced in performing FMT, which has been described as “a low-cost, low-risk, highly effective treatment” by The Fecal Transplant Foundation. In fact, Dr. Kunde is the first doctor in the United States to conduct a clinical trial to study the use of FMT on children with ulcerative colitis. His study showed positive results, proving that FMT could help some children with this condition as well.
The goal of FMT is to eliminate the C. diff infection by restoring good bacteria in the GI system. We have a repository of frozen fecal material obtained from healthy donors (http://www.openbiome.org/) who have been screened and tested for various infections to ensure the safety of this procedure. FMT is performed using a colonoscopy, where healthy donor fecal material is instilled into patient’s colon. With nearly 90 percent success rate, FMT is clearly a treatment option that should be at least considered and discussed for recurrent C. diff infection.
For more information on Dr. Kunde and WakeMed Physician Practices – Pediatric Gastroenterology, or call our office at 919-235-6435.