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To protect the health and wellbeing of our community, no visitors are allowed into our hospitals until further notice.
Limited exceptions may be made. Learn more.

Now offering virtual visits for all WakeMed Physician Practice primary care and specialties locations. Schedule an appointment today.

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Clinical Trials

The WakeMed Clinical Research Institute (CRI) conducts human studies (clinical trials) of the most promising new treatments and advances in many medical conditions, including heart and vascular disease.

Many study participants receive no-cost medical exams and ongoing assessments and diagnostic testing, no-cost study medications and medical devices, and financial compensation and/or travel reimbursement.


WakeMed is currently conducting a number of clinical trials looking at heart and vascular disease, including:

  • Hybrid Revascularization for Multivessel Coronary Artery Disease (HYBRID) trial: This clinical trial looked at the characteristics and outcomes of patients undergoing hybrid coronary revascularization (HCR) and multivessel percutaneous coronary intervention (PCI) for hybrid-eligible coronary artery disease.

  • VEST trial: This clinical trial examined the effectiveness of wearable cardioverter defibrillators in reducing sudden cardiac death among post-heart attack patients with left ventricular ejection fractions equal to or less than 35 percent.

Talk with your doctor if you are interested in participating in a clinical trial.