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Matthew Lyons, MD
208 ratings, 90 reviews
Practice Name
Hospital Preference
WakeMed Cary Hospital
WakeMed Raleigh Campus
Office Location
23 Sunnybrook Road
WakeMed Raleigh Medical Park, Suite 310
Raleigh, NC 27610
400 US Highway 70 East
WakeMed Garner Healthplex, Suite 205
Garner, NC 27529
Request an Appointment URL
400 US Highway 70 East, Suite 205
3024 New Bern Avenue, First Floor
23 Sunnybrook Road, Suite 310

Dr. Matthew Lyons is a urologist who specializes in minimally invasive and advanced robotic surgical techniques for the treatment of genitourinary cancers, benign prostate enlargement and urinary stone disease. He is an active participant in the Wake County GU oncology tumor board, which allows for a state of the art, multi-disciplinary approach to cancer treatment and collaboration with Duke medical oncologists, radiologists and radiation oncologists. This allows his patients access to cutting edge cancer care right here in Wake County. 

Additionally, Dr. Lyons specializes in men's health issues and offers advanced treatments for erectile dysfunction including prosthetic surgery, curvature of the penis (Peyronie's disease), including plication surgery and intralesional injection therapy with Xiaflex as well as treatment of low testosterone. Dr. Lyons also offers minimally invasive, single-incision, no scalpel vasectomy.

After graduating from medical school, Dr. Lyons continued his training by completing an internship in general surgery, and a residency in urology at the University of North Carolina at Chapel Hill. Dr. Lyons has published numerous research documents and abstracts on a wide range of urologic diseases and has presented his work at national and international meetings.


Dr. Lyons enjoys spending time with his family and his golden retriever "Ned", in addition to cheering on the Hurricanes and performing live music.?

"I believe in the relentless pursuit of exceptional patient care; the same care I would expect for myself or my family. I practice evidence-based urology and utilize the most recent advances in technology and clinical research to provide state of the art care to my patients.”

Care Philosophy
“I believe in the relentless pursuit of exceptional patient care; the same care I would expect for myself or my family”
Clinical Interests
Robotic and minimally invasive surgery for prostate cancer
Kidney cancer
Urothelial cancer
Urinary tract reconstruction
Advanced minimally invasive techniques for the management of urinary stone disease and enlarged prostate (BPH)
Treatment of men’s health issues including vasectomy consultation, low testosterone, erectile dysfunction and Peyronie’s disease, including prosthetic surgery
Undergraduate Degree
Washington and Lee University, Lexington, VA (Biology)
Medical School
Eastern Virginia Medical School, Norfolk, VA
University of North Carolina Hospitals, Chapel Hill, NC (General Surgery)
University of North Carolina Hospitals, Chapel Hill, NC (Urology)
American Board of Urology (Certified)
Professional Memberships
Endourological Society
American Urological Association
Star Rating

The Star Ratings score is the average score a provider receives about his or her care on our Patient Satisfaction Survey conducted by Professional Research Corporation. Learn more about our survey process. Responses are on a scale of 1 to 5 with 5 being the best score. The Star Rating you see represents the average score a provider received for the past 12-month period as long as they had more than 30 ratings during that time frame.

Overall Provider Rating
4.6 out of 5
208 ratings, 90 reviews

WakeMed Patient - April 2020

He is very kind. Have full understanding of my situation and discussed all the available treatment and intervention options available. 5 STARS

WakeMed Patient - April 2020

Everybody I came into contact with. The receptionist, the nurse the doctor and the lady who does the checkout process. The staff were very attentive and accommodating. Even with the whole Covid 19 situation going on. Everybody was very friendly and courteous.

WakeMed Patient - April 2020

The staff members there are always courteous, friendly, and professional.

WakeMed Patient - April 2020

Loved seeing the corona virus protections in place at the building entrance, checkin window, and waiting room very reassuring

Insurance We Accept

WakeMed contracts with most major health insurance carriers. View a list of Insurance we accept.

Before scheduling an appointment with either a WakeMed employed provider or a community-based affiliated physician, we encourage you to contact your insurance company to verify that the location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co-insurances, or deductibles that will be your responsibility.

If you are uninsured, learn more about WakeMed's financial assistance policy.