Thrombolytics & t-PA

H2H Summer 2012 Stroke Brain

Thrombolytics:  t-PA

WakeMed Primary Stroke team providers intravenously administer a thrombolytic drug called tissue plasminogen activator (t-PA) to help reestablish blood flow to the brain in the case of ischemic stroke.  When t-PA is administered, it interrupts the stroke and prevents the loss of nerve cells.

The Need for Speed

It's important to call 911 immediately when symptoms of stroke (slurred speech, confusion, weakness on one side of the body, vision loss) strike. Studies reveal that t-PA is most effective when it is administered within three hours of the onset of symptoms.

Patients who receive t-PA are 30 percent more likely to have minimal or no disability at 90 days after a stroke. In terms of stroke recovery after three months, the administration of t-PA at one hour after stroke symptom onset is 3.5 times more effective than administration at three hours after symptom onset.