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Translocation

Definition

Translocation means a change in location. It usually refers to genetic translocations, in which part of a chromosome is transferred to another chromosome. This type of translocation results in changed and often flawed chromosomes. In another type of translocation, two chromosomes will trade pieces with each other.

Genetic translocations can cause serious disorders, including chronic myelogenous leukemia.


Review Date: 8/11/2009
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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